SiroBoon 5mg Tablet (Sirolimus)

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Product Code:
Country of Origin :
Dosage Form :
Indication :
Prevention of kidney transplant rejection
Packaging :
10 tablets in 1 strip
Active Ingredient :
Manufacturer :
Kachhela Medex Pvt. Ltd.
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Product of India
Manufactured by:
Kachhela Medex Pvt. Ltd.

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Sirolimus 5mg Tablet is an immunosuppressant drug used along with other medicines to prevent the body from rejecting a kidney transplant. This medication is not suggested for use in children less than 13 years of age.

Sirolimus is used with other medications to stop the rejection of a kidney transplant. This medication belongs to a group of drugs known as immunosuppressants. It works by debilitating your body's defense system (immune system) to help your body receive the new organ as if it were your own.

It may also be used to treat a particular lung disease (lymphangioleiomyomatosis-LAM).

Organ Transplant - Rejection Prophylaxis

This medicine is used to prevent the rejection of an organ transplant.

Pulmonary lymphangioleiomyomatosis

This medication is used in the treatment of Pulmonary lymphangioleiomyomatosis, a condition which affects the lungs of especially women of childbearing ages, leading to progressive lung dysfunction.

Sirolimus 5mg Tablet suppresses the activity of the body's immune system and prevents rejection of the transplanted organ.

Take this drug in the dose and duration as proposed by your doctor. Consume it as a whole. Do not chew, crush or break it. Sirolimus 5mg Tablet may be used with or without food, but it is preferable to take it at a fixed time.

Missed Dose

If you miss a dose of Sirolimus 1 mg Tablet, take the missed dose as soon as you recall. If it is about time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.


Take emergency medical treatment or contact a doctor immediately in case of an overdose.

  • Hypersensitivity
  • Unusual bleeding or bruising
  • Cough
  • Cracked or scaly skin
  • Abdominal and stomach pain
  • Constipation or diarrhea
  • Nausea
  • Upper respiratory tract infection
  • Urinary tract infection
  • Difficulty in breathing
  • Jaundice
  • Tinnitus
  • Nervousness and confusion

General Instructions

Take Sirolimus 1 mg Tablet as suggested by your doctor. Do not take in larger amounts than suggested or share this drug with others. Verify that the treatment course is completed. Do not terminate the use of this medicine without confirming your doctor.

When Not to Use?


This medicine is not suggested for use in patients with a known allergy to generic drug sirolimus or any other components there along with it.

General warnings

Use in pediatrics

This medication is not recommended for use in children less than 13 years of age.

Blood pressure

This drug may cause an increase in blood pressure. Close monitoring of blood pressure is required during treatment with this medicine.

Use of contraception

Women of labor age are counsel to utilize adequate contraception before, during, and for 12 weeks following treatment with this drug to avoid pregnancy. This drug may cause serious side effects in the fetus.

Warnings for special population


This medication is not recommended for use in pregnant women unless necessary. Discuss all the risks and advantages with your doctor before taking this medicine.


This medicine is not recommended for use in breastfeeding women unless necessary. The risks and advantages should be discussed with the doctor before taking this medication.

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Is it dialyzable?

It is not dialyzable to a notable extent. i.e., it will not be removed after dialysis.

Is it a calcineurin inhibitor?

It is not a calcineurin inhibitor, but it has a similar suppressive effect on the immune system.

Is it cytotoxic?

It is a cytotoxic agent.

What is Sirolimus-eluting stent?

The Sirolimus-eluting stent is a metal stent coated with 140 µg/cm2 of Sirolimus blended with synthetic polymers. After stent implantation, it is slowly released causing contained inhibition of growth of smooth muscle cells in the wall of the blood vessel in which it is implanted throughout about one month.

Does it cause hair loss?

It causes hair loss.

Why does it cause hyperlipidemia?

It alters specific body pathways to increase lipid/fat synthesis by the liver, thereby causing hyperlipidemia.

Is this drug or product addictive or habit forming?

Most medicines don't come with the potential for addiction or abuse. Usually, government's categorizes medicines that can be addictive as controlled substances. Examples include schedule H or X in India and schedule II-V in the US. Please consult the product package to make sure that the medication does not belong to such individual categorizations of drugs. Lastly, do not self-medicate and increase your body's dependence on medicines without the advice of a doctor.

Can it be stopped instantly or do I have to wean off consumption slowly?

Some medicines need to be attenuate or cannot be stopped immediately because of rebound effects. Please confer with your doctor for recommendations specific to your body, health and other medications that you may be using.

Is it safe to drive or work heavy machinery when swallowing?

If you feel drowsiness, dizziness, hypotension or a headache as side-effects when using this tablet, then it may not be secure to drive a vehicle or operate heavy machinery. One should not drive a vehicle if using the medication makes you drowsy, dizzy or lowers your blood-pressure extensively. Pharmacists also propose patients not to drink alcohol with medicines as alcohol intensifies drowsiness side-effects. Please check for these effects on your body when using Sirolimus Tablet. Always consult with your doctor for recommendations certain to your body and health conditions.

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