Falcigo Injection (Artesunate)

Buy Falcigo 60mg,120mg Injection Generic drug of Artesunate online at a low price from most trusted pharmacy to cure Malaria. Get all info about this medicine like the review, use, side effect, dosage (missed/over), how long does the last, Composition, Substitutes, manufactured by Zydus Cadila Pharma, how it works, Precautions and many more. You can also get speedy delivery in the UK, USA, Australia, France, China.

Falcigo 60MG and 120MG injections contain artesunate which is a water-soluble hemisuccinate derivative of artemisinin, (qinghaosu), an antimalarial principle extracted from leaves of the plant Artemisia annua. Also sesquiterpene lactone peroxide. It is an odorless, white crystalline powder, and almost tasteless. The chemical name of Artesunate is Dihydroartemisinin-10-ol hydrogen succinate.it’s Chemical Formula is a C19H28O8. Zydus Cadila Pharma.it manufactures this medicine a composition of Artesunate; it is an active Ingredient.The pack contains: 2 ml ampoule of sodium, Bicarbonate Injection IP 5.0% w/v ,10 ml ampoule of Sodium Chloride Injection IP 0.9% w/v.

Falcigo 120mg injections are indicated for the treatment of severe malaria including cerebral malaria and as a second line treatment in chloroquine-resistant malaria. They should not be used as a first-line treatment of malaria.

Plasma tranquilize focus diminishes quickly after the intravenous organization of artesunate. The plasma half-life is about 30 min. It distributes widely through the body and with a high level in intestines, liver, and kidneys. Only small quantity is excreted in the urine and the stools. It is mainly eliminated by metabolic biotransformation.

Clinical effectiveness of artemisinin compounds been confirmed in P.vivax and P.falciparum malaria (both in chloroquine-sensitive and -resistant strains). Artemisinin mixes are quickly acting blood schizonticides for these species. They work early in the asexual parasite developmental cycle by destroying the early ring forms. They have no work on persistent hepatic forms and gametocytes. Their power in other species of malaria, i.e., P.ovale and P.malariae are yet not thoroughly evaluated.

Artemisinin compounds are concentrated in parasitized erythrocytes. Endoperoxide bridge is essential for antimalarial activity. They are thought to cause free radical damage to the parasite membrane system, although the precise mechanism is unclear. Artemisinin compounds act rapidly stopping parasite development and preventing subsequent cytoadherence.

A 15ml vial containing 120mg Artesunate with a 2ml ampoule of Sodium Bicarbonate injection IP 5.0% w/v and a 10ml ampoule of Sodium Chloride injection IP 0.9% w/v. Store below 30℃ and Protect from Light. The proper information about how long does it last is printed on the bottle.

Falcigo 120 injections are for intravenous and intramuscular use.

The usually recommended dose of the drug is 2.4mg/kg (i.e., 120mg in adults) given initially and then repeated after 12 and 24 hours and once daily after that. The usual duration of the treatment is five days. The duration of treatment is seven days in severe and non-immune patients. The recrudescence rate is <10% in chloroquine-resistant areas.

Before administration, artesunate powder is mixed with 2 ml of 5.0% sodium bicarbonate and shaken for 2-3 minutes. After it dissolves completely and the solution becomes clear. Air is eliminated from the vial with a syringe and needle.

For I.M. use, add 4 ml of 5.0% Dextrose or normal saline to make a final concentration of 20 mg/ml of artesunate. Inject by IM route slowly.

It ought to be infused all of a sudden after the powder of artesunate breaks down. If the arrangement seems overcast or residue happens, it ought not to be utilized. It ought not to be used as intravenous implantation.

Missed Dose

Contact your doctor immediately if you miss a scheduled dose of Falcigo 60mg and 120mg injections.

OverDose

Contact your family doctor immediately if an overdose with this medicine is suspected.

According to expert reviews, No adverse reactions have been observed with the recommended dose till now. Transient reticulocytopenia may occur when dose more than 3.75 mg/kg is given.

Minor side effect

• Dizziness
• A headache
• Abdominal pain
• Diarrhea
• Injection site pain
• Fever with body pain

Major side effect

• Anemia
• Low WBC and Platelet count
• Swelling of the liver

General Instructions

There are results of animal experiments have shown some embryotoxic effects. Therefore, it should be used with extreme cautions in pregnancy within the first three months.

When not to use?

Allergy

These Falcigo 60mg injections are not recommended for use in patients with a known hypersensitivity to this drugs or any ergot alkaloids or any other components present along with it.

General warnings

Severe malaria

This medicine should be used to treat disease only when it is cruel, and other drugs like quinine are proving to be ineffective.

Medicine induced fever

This medicine can cause illness as a side effect.

Liver/kidney impairment

This drug should use with caution to suffer having an impaired liver/kidney function. If the impairment is very severe, then the use of this medicine should be avoided.

Warnings for special population

Pregnancy

This Falcigo 120 injection are considered safe for consumption by pregnant women. However, all the benefits and risks should be discussed with the family doctor before taking this medicine. This medicine is not recommended for a pregnant lady.

Breastfeeding

This medicine is not recommended for breastfeeding women.

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