Trustiva tablets in their essence are a combination of three antiretroviral drugs namely efavirenz, emtricitabine, and tenofovir disoproxil fumarate. Each of the medicines acts together combating various conditions so the virus cannot replicate itself and destroy the immune system. Their basic plan of action is to hinder or stop the effects of an enzyme known as Reverse Transcriptase (RT). This enzyme is essential for the virus to multiply and attack the body’s immune system and by managing it; the medication can control the infection. the proper information about how long does last is provided in the tablet strip or tablet box.
Efavirenz is an inhibitor that binds to a particular site on the RT enzyme. Moreover, in doing so, the antiretroviral drug stops the actions of the protein without conflicting or competing with nucleosides. This prevents the virus before it is converted from RNA to DNA and stops the infection from growing.
This is why Efavirenz is classified as a non-nucleoside reverse transcriptase inhibitor or NNRTI. In the case of Emtricitabine and Tenofovir, they employ the principle of chain termination. They compete with the nucleosides, and they get embedded in the newly formed DNA. By doing that, the drugs stop the chain of freshly formed infected DNA chains from going further. This inhibits the ability of the infection to replicate, and the infection stays under control.
