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cyproterone acetate ethinyl estradiol 

Cyproterone acetate 2.00 mg Ethinylestradiol 0.035 mg coated tablets

Cyproterone acetate/Ethinylestradiol

This medicine is subject to additional monitoring. This will allow quick identification of new safety

information. You can help by reporting any side effects you may get. See the end of section 4 for how to

report side effects

Read all of this leaflet carefully before you start taking this medicine because it contains

important information for you.

    • Keep this leaflet. You may need to read it again.
    • If you have any further questions, ask your doctor pharmacist or nurse.
    • This medicine has been prescribed for you only. Do not pass it on to others. It  may harm them, even if their signs of illness are the same as yours.

If you get any side effects,talk to your doctor, pharmacist or nurse. This includes any

possible side effects

What is in this leaflet:

1. What Cyproterone/Ethinylestradiol tablets are and what they are used for

2. What you need to know before you take Cyproterone/Ethinylestradiol tablets

3. How to take Cyproterone/Ethinylestradiol tablets

4. Possible side effects

5. How to store Cyproterone/Ethinylestradiol tablets

6. Contents of the pack and other information

 1. What Cyproterone/Ethinylestradiol tablets are and what they are used for

Cyproterone/Ethinylestradiol contains an oestrogen and an anti-androgen.

Cyproterone/Ethinylestradiol is used to treat skin conditions such as acne, very oily skin and excessive hair growth in women of reproductive age. Due to its contraceptive properties it should only be prescribed for you if your doctor considers that treatment with a hormonal contraceptive is appropriate.

    • You should only take Cyproterone/Ethinylestradiol if your skin condition has not
    • improved after use of other anti-acne treatments, including topical treatments and antibiotics.
    • If you are taking Cyproterone/Ethinylestradiol for skin treatment, you must not take any other hormonal contraceptive at the same time.
    • When your skin condition has cleared up and you stop taking Cyproterone/Ethinylestradiol

Treating skin conditions

Androgens are hormones that stimulate hair growth and the grease glands in your skin. If you produce too much androgen, or if you are sensitive to the effect, the grease glands may produce too much sebum. This can block the grease glands, which can become infected and inflamed causing acne spots. Cyproterone/Ethinylestradiol stops the androgens affecting your skin and reduces the amount of androgens produced.


Cyproterone/Ethinylestradiol is a 21-day Pill – you take one each day for 21 days, followed by 7 days when you take no pills.

Cyproterone/Ethinylestradiol will not protect you against sexually transmitted infections, such as Chlamydia or HIV. Only condoms can help to do this.

Cyproterone/Ethinylestradiol needs to be taken as directed to prevent pregnancy.

2. Before you take Cyproterone/Ethinylestradiol tablets

It’s important that you understand the benefits and risks of taking Cyproterone/Ethinylestradiol before you start taking it, or when deciding whether to carry on taking it. Although Cyproterone/Ethinylestradiol is suitable for most healthy women it isn’t suitable for everyone.

    • Tell your doctor if you have any of the illnesses or risk factors mentioned in this leaflet.

Before you start taking Cyproterone/Ethinylestradiol

pressure and exclude the likelihood of you being pregnant. You may also need other checks, such as a breast examination, but only if these examinations are necessary for you or if you have any special concerns.

    • While you’re on Cyproterone/Ethinylestradiol
    • You will need regular check-ups with your doctor, usually when you need another
    • prescription of Cyproterone/Ethinylestradiol.
    • You should go for regular cervical smear tests.
    • Check your breasts and nipples every month for changes – tell your doctor if you can see or feel anything odd, such as lumps or dimpling of the skin.
    • If you need a blood test tell your doctor that you are taking Cyproterone/Ethinylestradiol, because this type of medicine can affect the results of some tests.

When should you contact your doctor

Stop taking tablets and contact your doctor immediately if you notice possible signs of a blood clot. The symptoms are described in section 2 ‘Blood clots (Thrombosis)’.

Cyproterone/Ethinylestradiol also works as an oral contraceptive. You and your doctor will have to consider all the things that would normally apply to the safe use of oral hormonal contraceptives Blood clots (thrombosis)

Taking Cyproterone/Ethinylestradiol may slightly increase your risk of having a blood clot (called a thrombosis). Your chances of having a blood clot are only increased slightly by taking Cyproterone/Ethinylestradiol compared with women who do not take Cyproterone/Ethinylestradiol or any contraceptive pill. A full recovery is not always made and in 1-2% of cases, can be fatal.

Blood clots in a vein

A blood clot in a vein (known as a ‘venous thrombosis’) can block the vein. This can happen in veins of the leg, the lung (a lung embolus), or any other organ.

Using a combined pill increases a woman’s risk of developing such clots compared with a woman not taking any combined pill. The risk of developing a blood clot in a vein is highest during the first year a woman uses the pill. The risk is not as high as the risk of developing a blood clot during pregnancy.

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